Found Malar Rash on your face, Beware of Lupus Erythematosus

There is a malar rash on your face? Beware Lupus Erythematosus!

What is lupus erythematosus?

 Lupus Erythematosus is a disease of the immune system characterized by the production of antibodies against the core components of body cells. This disease is also called Systemic Lupus Erythematosus (hereinafter abbreviated to SLE).

SLE rheumatic disease that also includes quite a lot of discussion in the world. This disease mostly affects women. Comparison between men and women about 1:5.

 There are some particular race that often suffer from SLE, among other negro nations, China and possibly the Philippines. And SLE is found at any age, but cases are often found around age 15-40 years.

Signs and symptoms of "SLE"?
The most commonly known signs of SLE is the appearance of a red rash on the face that is similar to a butterfly. Usually if you have found cases of patients with signs like that, most likely the patient is suffering from SLE.

 

 

Other signs or symptoms of SLE has been declared by the "American College of Rheumatology" is 11 criteria for the classification of SLE. The eleven criteria include:

• Malar rash

• Discoid rash

• Photosensitivity (sensitivity to light)

• Ulcerations (sores sort of) in the mouth or nasopharynx

• Arthritis

• Serositis (inflammation of the serous membrane), which is pleurisy (inflammation of the pleura) or pericarditis (inflammation of the pericardium)

• Kidney disorders, namely proteinuria (protein in the urine) persistent> 0.5 g / day

• Neurologic abnormalities, ie convulsions

• Hematologic abnormalities, ie hemolytic anemia or leukopenia

• Immunologic abnormalities, which found a positive LE cells or anti-DNA positive

• Presence of antinuclear antibodies.

In addition, other symptoms or signs that are often found among other weight loss, fever, and bone disorders such as arthritis. 

Causes of Lupus Erythematosus

Almost all clinical manifestations due to Lupus Erythematosus effects of immune complexes in various tissues or direct effect of antibodies on the cell surface components.
Causes of Lupus Erythematosus there are many, including:

• The reduced activity of T suppressor cells and cytotoxic T

• T helper cells increases

• Decreased immune tolerance (it's been tested in experimental animals).

• Photosensitivity or light from the sun can trigger SLE in patients with active SLE back.

• Hormone estrogen is considered to be one of the factors in SLE.

Also suspected that the disease can be passed from mother to child. If a mother suffering from SLE, 2.5% chance of suffering from SLE daughter while opportunities for her son around 0.4%.

In addition, drugs can also trigger SLE. Or so-called "Drug-induced SLE" (drug-induced SLE). Mainly due to the side effects of drugs:

• hydralazine (Apresoline) for high blood pressure

• quinidine (quinidine sulfate, quinidine gluconate)

• procainamide (Pronestyl) for abnormal heart rhythms

• phenytoin (Dilantin) for epilepsy

• isoniazid (Nydrazid, Laniazid) for tuberculosis

• d-penicillanmine for rheumatoid arthritis

Although these drugs can induce SLE, but the incidence of cases of drug-induced SLE is quite rare.

Appropriate Therapy for SLE Disease

Therapy is based on the severity of SLE and systems of the body are involved. SLE patients with joint pain is usually recommended to take the drug acetaminophen or ibuprofen to relieve pain.

Another drug that is commonly used antimalarial drugs. In SLE patients, this drug is used to prevent and treat malaria (fever). And also found that antimalarial drugs also help treat SLE. Besides antimalarial drug is also beneficial for skin rash and pain in joints.

Another addition to SLE patients are vitamin D supplements. Because SLE patients are strongly encouraged to avoid the sunlight. That's why to avoid bone loss SLE patients given vitamin D supplements.

Actually almost no drugs actually cure SLE. That there are only drugs that treat only the symptoms of SLE. SLE patients least able to survive.

Complications of SLE

Some complication of SLE that include:

• vasculitis (inflammation of the veins)

• pericarditis

• myocarditis

• hemolytic anemia

• intravascular thrombosis

Glucocorticoids also known as one of the choice of drugs for SLE patients. However, these drugs can also aggravate the condition of SLE if given with high doses.

How to prevent SLE
Patients with SLE can actually live a normal life as long as it is able to prevent or protect themselves from the causes or triggers of SLE. The things that can be done include:

• Avoid excessive sun. If out of the house during the day make it a habit to use an umbrella or a hat. Clothes are long-sleeved clothing is recommended. For those of you who are office workers avoid sunlight from the window.

• Get enough rest and avoid activities that are too busy are also useful.

• Eating healthy foods and exercising regularly.

• Avoid infections such as infection of the tattoo or other infections. Because most drugs for SLE suppress the immune system, so it is expected that patients with SLE to avoid infection.

• For girls is highly recommended to not consume drugs containing the hormone estrogen. 

SOURCE REFERENCE:
-Leber, J Mark, MD, MPH, FACEP (October 2009). "Systemic Lupus Erythematosus", http://www.emedicine.com
-Burch, Joanna M, MD. "Neonatal Lupus Erythematosus", http://www.emedicine.com- Disease Specialist Doctors Association of Indonesia. "Textbook of Medicine". IPD FKUI Publishing Center. Jakarta. 2007: 1214-1221. 

Found Malar Rash on your face, Beware of Lupus Erythematosus 2013-08-11T21:12:00-07:00 Rating: 4.5 Diposkan Oleh: Unknown